Thursday, September 26, 2019

Critical Book Review Essay Example | Topics and Well Written Essays - 1500 words

Critical Book Review - Essay Example This essay presents a critical review of Many Lives, Many Masters in order to investigate the area of reincarnation as explored by Dr. Weiss through his session with his patient Catharine. The covers some of the proofs presented by doctor Weiss in order to confirm his changed beliefs on reincarnation followed by an analysis of both the strengths and weaknesses of the authors argument before making suggestions on future investigations into the area and ending with a brief conclusion. This book by Weiss (1988) shades more light in the area that has garnered widespread discussion thorough his sessions with a 27 year old Catherine during the 1980 as he seeks assist her overcome her deep-seated anxiety, panic attacks and phobias. As a graduate from the Yale University School of Medicine where he also went through his residency in psychiatry in addition to serving as Chairman of Psychiatry at the Mount Sinai Medical Center in Miami, Dr. Weiss is a psychiatrist trained in the scientific met hods of dealing with psychological problems that his patients present during his sessions. Therefore, based on his original training as a psychiatrist doctor Weiss had always followed the conservative paths of his profession and was a skeptic when it came to exploring other methods of psychological healing but that was prior to meeting Catharine who changed his views on reincarnation of the human soul. The sessions between Dr Weiss and Catharine lasts for over 18 months where the doctor applies conventional techniques to cure her problems without success. However, doctor Weiss attempts a series of hypnotic trance states on Catherine; she begins recalling past life memories that could be attributed to be the factors causing her symptoms which effectively lead to her cure within a few months. At the initial stages of the hypnosis, Catharine doubted the ability of the technique to dig out the answers she was searching for given that she did not believe in reincarnation but after a numb er of such sessions, Catharine realized she acted as a medium for secrets of life and death from spirits that had evolved over many lives and could not only talk about Catharine’s past lives but also about her doctor’s life. Dr. Weiss uses his sessions with Catharine to reveal how much he learned about life and the nature of human soul which is able to live after death of the body. Through Catherine's disclosures under hypnosis, the doctor reveals incidents that occurred in some of the 86 lives Catharine had lived on earth as a unique soul that was born across different times and places where she confers with masters that helped her to see the lesson learned from the life just lived. Catharine’s revelations are guided by the masters who according to what Weiss (1988) presents are the sages at the highest plane spiritual evolution and are capable of offering lasting wisdom teachings that extend back into all the history of humanity and traditional cultures. The m asters state the purpose of living, according to Catharine’s revelation as being to learn and grow through seeing the spark of God in others and ourselves as the guiding principle for the survival of the soul and continued cycle

Wednesday, September 25, 2019

Geography The discussion in this class goes around (How Societies Assignment

Geography The discussion in this class goes around (How Societies Change) - Assignment Example ld lost his motors workshop which was operating quite soundly and he was hoping to employ two people but lost it to the tornado and many others like him have suffered a lot. The geographic location of the town became a hindrance in the peaceful life of the town but nature cannot be fought and people just have to wait until the disaster is over. â€Å"Lifeline connects state known as shifting sands (The New York Times, 2012).† Another geographic challenge faced by the US authorities as published in The New Times on 5-Mar-12, Hatteras’ lifeline the only bridge known as â€Å"Highway 12† connecting the small island with the world was trashed by hurricane Irene. The local authorities built the bridge afresh but nature seems to oppose the construction, winds and waves are still causing it harm spreading fear that it might not sustain and collapse again. This place is also stricken by its geographic location with a deadly ocean around it. These natural disasters can destroy lives and property while humans can do nothing to control them. Man seems powerless in front of such disastrous geographic changes. These disasters prove lethal to the economy and the infrastructure of the state, reconstruction cost millions and people having lost their precious properties are under heavy stress by the effects they encounter. Although people have settled down in these places and have adopted their lives following the geographical dangers of the place yet when it strikes the people can do nothing but watch helplessly at the poor state they are left in after the disasters. Economic situation is crushed and people seem crushed to poverty. Without homes they have to spend their days out on the streets and sleep under open sky or in their cars instead of their cozy beds. Life seems to be sucked out of them. With businesses destroyed it becomes a challenge for the people to re-establish themselves and the jobless people live a life of refugees in their very own city. With no money,

Tuesday, September 24, 2019

ISO 14000 Essay Example | Topics and Well Written Essays - 250 words - 1

ISO 14000 - Essay Example Industrial waste is the largest contributor to the environmental pollution; it is an unwanted by-product of the raw materials. It is the utmost responsibility of the corporate to dispose of this materials that the contamination to the nature i.e. air, water and soil to the least levels. Recycling is also regarded as the most preferred â€Å"waste management strategy† (Cheremisinoff,2001). Along with it local and community based initiatives should be taken to control the emission of toxics from the waste. Researchers suggest that prevention from the pollution, by the usage of less pollution producing products, helps the organization to increase the efficiency, this also boosts the financial stability of the company (Maystre and Spiegel, 2011). In order to make the corporate to put in the right amount of efforts the consumers as well as the government also needs to play in their role and should force the corporations to take the right

Monday, September 23, 2019

Assignment Essay Example | Topics and Well Written Essays - 500 words - 50

Assignment - Essay Example As much as layoffs are not a desirable state of the organization, it is always important for the employer to communicate to the employees about it openly instead of letting them get to learn about it through rumors and other means (Business & Legal Reports, Inc., 2009). In the case of the employee who comes for advice amidst such layoff rumors, I would advice them by doing the following: Provide honest and accurate information regarding the layoff to the affected employee. First, it is important to clarify whether the rumor regarding the impending layoff is true or false. Second, I would clarify the reasons and benefits of the payoff to both the employee and the organization. Third, I would help the employee to gain an understanding of the picture of the company following a layoff. Fourth, I would let the employee know how the layoff will take play; whether it is temporary, permanent or in phases. Lastly, I would let the employee know whether there would be any financial resources and support provided incase of the layoff. The Provision of accurate information will enable the employees feel that they are valued, are kept in the loop and that they participate in the decision that affect their lives. Once the employee has attained a clear picture of the situation, I would seek to gather information on how he or she perceives the upcoming layoff. This information is critical because it will enable me to understand how the employee is affected by the layoff rumor, whether this is likely to affect the performance of the ongoing project, issues affecting the employee during the planned layoff and whether the employee has already had job offers elsewhere. After getting the perspective of the employee, I would try to manage his attitudes and behavior about the layoff. I would let the employee know that he or she is very important to the organization although the layoff is inevitable. I would advice the

Sunday, September 22, 2019

Career Services Essay Example | Topics and Well Written Essays - 750 words

Career Services - Essay Example For hopeful employees, it is important to connect to a network through which they can get information about openings especially those that may not be advertised in mainstream media. In addition, volunteering is proposed as an effective way of improving ones chances of getting a job since they get a chance to create a rapport with the organisations and ultimately if there is an opening in the firm, they will likely be considered. While admitting that most graduates would prefer to earn a salary, volunteering is a way for them to work in a field that they are passionate about. This way, they can get these hidden jobs, which according to the writer are not really hidden after all, but just require creativity and sacrifice to get. In my opinion, this is as close to the truth as it gets, people assume that the job market is saturated and even as they leave college, many are already pessimistic about their prospects. Others imagine that the jobs are only available for the lucky few. However as the writer says, luck in the job market has nothing to do with superstition or coincidence, quite on the contrary, luck is directly proportional to how hard one works or the extent to which they expose themselves to opportunities (Thomas). For example, a fresh graduate out of college will likely go online and start looking for positions that best match their paper qualifications. In many cases, one may have undergraduate and even a master’s degree in a field such as business management and they will actually expect to apply for managerial positions on the entry level for which they will generally be qualified to save for perhaps the experience part. However, most of them will be frustrated, as they will keep being passed over for positions. However, every once in a while one runs into a colleague who left college at the same time as they, 4 years after college and they have a good

Saturday, September 21, 2019

Roles of an addiction counselor Essay Example for Free

Roles of an addiction counselor Essay An addiction counselor has many roles; counselor is only one of them. Others include interventionist, mediator, advocate, change agent, adviser, and facilitator (Lecture Module 4, 2013). While treating a client those roles are constantly changing and are necessary to help a client to overcome addiction. In addition the counselor must be able to maintain a balance of ethical, moral, and legal behavior while treating their clients. This may seem easy; however there are often blurred professional boundaries present that the counselor is forced to navigate flawlessly or risk upsetting the balance between helping and hurting their client. While an addiction counselor’s main goal is to improve the mental health and wellness of clients through a treatment plan the goals need to be based on the individual the counselor is working with; therefore each case must be individualized to meet the needs of the client. Individual therapy consists of working directly with an individual, an assortment of approaches are used in individual therapy. The approaches include harm reduction, coping skills training, life-skills training, motivational interviewing, cognitive-behavioral therapy, social skills training, and behavior therapy these approaches are included in the direct effect strategies as well as the broad spectrum strategies. The central component to these strategies is the client- counselor relationship also known as the therapeutic alliance. The counselor must be able to listen objectively to the client, they must be aware of their responses not only verbally but non-verbally as well. They must be able to validate the client through non-verbal communication as well as positive regard. The language the counselor uses must engender motivation toward change for the client. By moving away from negativity these strategies give the clients hope and breed independence which leads to abstinence. These strategies are imperative to the success of the client and the counselor is the facilitator of this. Individual therapy consists of creating an environment where lifestyle changes can begin, the therapeutic relationship is a partnership in which the counselor facilitates change with the client (Smith Stevens, 2013). When working in a group many of the same approaches are used; however a counselor must now be able to use the strategies in broad form to reach all of the members of the group. Groups are more focused on the here and now; because there is a time limit they must be able to stay focused in order to make progress. A group setting gives a client a bigger base of support; however the counselor must be able to provide culturally diverse guidance to all of the group’s members. This can often be challenging, so the group counselor should be a highly trained individual. A rapport must be established with the group so that trust can be built and cohesion will occur. The cohesion of the group takes precedence over the individual needs of clients (Smith Stevens, 2013). There may be times when a counselor acting as an advocate for the group must remove a member for the greater good of the group. Group development can be considered in terms of stages or phases; the group can become more complex and resourceful over time with sufficient leadership and member investment. It is also important to note that clients should receive pretreatment as an individual in order to prepare them to become productive members of a group and to receive maximum benefits from the process (Smith Stevens, 2013). Relational therapies involve individuals and intimate others in the group process to examine bonding and boundaries (Smith Stevens, 2013). This type of therapy group can help individuals, couples, and families avoid dynamics that contribute to replay of unfinished business or relapse. The role of the counselor is to create a therapeutic alliance through creating a safe and honest environment by which the client’s family can support each other. In this type of therapy each member of the group must be allowed to share their feelings to essentially cleanse the environment of past resentment and to start fresh. Families often avoid dealing with the problem of drug or alcohol abuse they would rather hide it than deal with it. The counselor must be able to root out the pattern of abuse so that the family can work to change it. This can be hard because the counselor must be careful about being overly critical of the client this could cause the family to turn on the counselor and become counterproductive. Addiction encompasses every aspect of the client’s life this includes their family, it is imperative to address the patterns that exist within the family not only to help the client but also to prevent future generations from having the same issues. There are many soft skills that a counselor must possess in order to be effective. One of the biggest is empathy; empathy requires that the counselor be able to feel how the client must feel and to communicate understanding in order to help the client move past the addiction. The counselor must show warmth by showing they care what happens to the client. Listening is paramount as well; the counselor should create an environment where the client wants to share their story. By doing this the counselor builds a trusting relationship where the client feels safe from judgment. The counselor must exhibit communication skills being able to redirect when necessary, verbal and non-verbal communication must be on point. The counselor must also be able to maintain a professional and ethical position with the client. The counselor must see the client as a human being worthy of help; accept the person not the behavior (Doyle-Pita, 2004). When all of these skills are employed to help a client the many roles a counselor must facilitate will be more easily navigated and the client will be more likely to achieve success.

Friday, September 20, 2019

Determination of Sodium Thiopental Using Gold Nanoparticles

Determination of Sodium Thiopental Using Gold Nanoparticles Development of a new colorimetric method for the determination of sodium thiopental using gold nanoparticles Sodium thiopental (sodium pentothal) is in a group of drugs called barbiturates.this barbiturate commonly used anesthetic induction agents in man and animals because recovery is rapid and it has the advantage of having very little or no side effects[1].It is used for intensive-care patients with head injuries to control convulsions and reduce raised intracranial pressure[2]. As a resultmonitoring of theserum concentrations is important in this patient population. Several analytical procedures have been reported for the quantitative determination of thiopental. Among these high-performance liquid chromatography (HPLC) are more popular. HPLC assays are not completely reliable, and do not have the short process-time required in most of the above-mentioned indications[3, 4]. other methods are available for determining thiopental including stripping voltammetry[5],membrane sensors[6],capacitive chemical sensor [7],gas chromatography (GC)[8],spectrophotometric and spectrophotofluorometric[9, 10]. Donald et al[11]reported that, after the usual 4.8 mg/kg induction doses, thiopental concentration in serum as a function of time varies between 10 mg/L to 25 mg/L during 50h.As stated before most of these currently used methods for sodium thiopental detection usually need expensive and complicated instruments and are time-consuming, making on-site and real-time thiopental detection difficult. Therefore, it is important to develop a simple reliable and hig hly sensitive method for on-site and real-time detection of sodium thiopental. Recently, gold nanoparticles (NPs) explored for metallic NP-based colorimetric detection have attracted considerable attention due to biocompatibility, stability, and high extinction coefficients[12]. gold nanoparticles present size-dependent optical properties owing to the surface plasma resonance(SPR)[12]. The color of the colloidal Au NPs can be readily and precisely changed via aggregation of Au NPs.Au NPs were widely applied in colorimetric detection of several analytes such as protein, DNA, metal ions and small molecules[ ]. In this study, we used gold nanoparticles as a colorimetric probe for sensitive and selective detection of sodium thiopental. The gold nanoparticles were prepared using the classical citrate method [12].thiopental on the surface of AuNPs displaced the stabilizing citrate ions because thiol group of sodium thiopental tends to readily adsorb onto the surface of colloidal gold via chemisorptions-type interactions. The thiopental capped Au NPs were stable at basic and neutral conditions .Puntes et al [13] have studied the stability of cationic gold nanoparticle bioconjugates as a function of pH and the presence of citrate in solution. The pH of an aqueous solution of thiopental-Au NPs was varied by direct addition of citrate buffer. the thiopental-Au NPs can be aggregated by adding certain amounts of citrate buffer due to the electrostatic attraction between amino group contained in thiopental molecular and citrate ion on the surface of Au NPs, the amino group of the thiopental would be positively charged at the given pH value and they would therefore interact electrostatically with the negative charges of the citrate molecules. Thus forcing the aggregation of the conjugated Au NPs and subsequently resulting in the color change from wine red to purple or blue color.So that we detected it by UV–Vis spectrophotometer and paptode techniques and contrast both methods.First time at 2004 paptode was developed in Dr. Abbaspour group for speciation of iron(II) and iron(III) and the full range pH monitoring [14]. Then it was used for the determination of dopamine [15], hydrazine [16]. In paptode, conventional à ¯Ã‚ ¬Ã¢â‚¬Å¡atbed -scanner (as a nondestructive detector) was used to acquire the analytical parameters for quantitative determination of analyte that occurs via colorimetric reaction. The estimated re à ¯Ã‚ ¬Ã¢â‚¬Å¡ection density, as an analytical parameter, is obtained from an area of the sensing zone of spots using the average Red (R), Green (G) and Blue (B) channel. Degrees of the color of the spots are found to be proportional to the concentration of the testedanalyte. Experimental section: Reagents: HAuCl4.3H2O, trisodium citrate and citric acid were purchased from Sigma. Thiopental was obtained from Biochemie (Kundl, Austria) and zinc sulfate purchased from Fluka All solutions were prepared with ultrapure water Apparatus and software: The colorimetric study of NPs were performed by means of a Shimadzu 1601PC UV–Vis spectrophotometer (Kyoto, Japan)from 300 to 700 nm. Also a Canon scanner were used to record the color changes in paptode technique. The paptode Cells were built by creation of the holes (i.d 1.5 cm) in the sheet of plexiglas (thickness 0.9 cm). We used by photoshop Cs6 software to convert the recorded pictures of color of cells to RGB (Red, Green and Blue) and L*a*b data. The morphology and size of the nanoparticles were characterized by a transmission electron microscope (TEM model CM10; Philips). The X-Ray diffraction (XRD) patterns were obtained by using a D8 ADVANCE type (BRUKER-Germany) with Cu-KÃŽ ± radiation (ÃŽ »= 0.1542 nm). Powder XRD patterns were taken in 0.02 ° steps at 1 s per step. All the experiments were carried out at room temperature(25  ± 2 C) Synthesis of citrate-stabilized Au nanocrystals: Nanoparticles of noble metal were prepared by classical citrate method[12].the10ml of 0.014M of trisodium citrate dehydrate solution was added quickly to the 100ml of boiling solution of 0.5mM of HAuCl4.3H2O under magnetic stirring. The stirring was continued until a dark red color was observed (around 20 min) and the maximum absorbance of AuNPs solution was centered at 520 nm Sample preparation: Fresh human blood samples (2.0 mL) were obtained from volunteers of the local hospital. After letting sample stand for 60 min at room temperature we centrifuged at 4000 rpm for 10 min. The supernatant was used as the source of the serum. We used zinc sulfate method as a deproteinization technique[]: we vortex-mix for 10s of the 10ml of serum sample and 150mg zinc sulfate, then we centrifuged the mixture at 3000 rpm for 20 min. The supernatant, which excluded protein, was used for further analysis. Procedures for the detection of sodium thiopental: In a typical detection of sodium thiopental, different amounts of thiopental solution were added to the above XmlAu NPs solutions at room temperature. we proceeded to study the behavior of the conjugated system by modifying the pH . To investigate the effect of pH of the buffer solutions on thiopental detection, 0.5 mL of 0.1 M buffer solution (citric buffer solution in the pH range of 3.0–6.0 ) was added in mixture of thiopental and Au NPs solution. The obvious color change was observed with the naked eye and the absorbance spectra and scanning images of the solution were recorded 1 min after the addition of citrate buffer. In spectroscopy technique ,The concentration of sodium thiopental was quantified by the absorption ratio (A670/A520). Results and discussion Citrate was chosen as the stabilizer for AuNPs because it is negatively charged, and can act as a stabilizingagent to disperse AuNPs in aqueous solutions. The Au NPs after synthesis showed a surface plasmon resonance (SPR) band at 405 nm (Fig. 1a). the addition of sodium thiopental doesn’t led to a color change of Au NPsin ultrapure water, although the thiol group of sodium thiopental tends to readily adsorb onto the surface of Au NPs.The pH of AuNPs solution in present of sodium thiopental is 10.2 and Puntes et al[13]reportedthat the presence of charged molecules insolution may induce NPs aggregation by bridging particlestogether. It was observed that multiple electrostatic interactions between the conjugates mediated by cross-linking species led to an effective strong bond and consequently to irreversible aggregation and precipitation. So that at the given pH value , charge of thiopental can be change and thenthe color of the colloidal thiopental-Au NPs can be changed to blu e (broad band above 600 nm).*Scrutiny of pH/Concentrate diagrams of citrate and thiopental shows that at the pH of between 5 to 7 , charge of citrate and thiopental can benegative and neutralfig S1. But when sodium thiopental add to AuNPs solution, the S- group in the sodium thiopental provides a strong affinity for gold. So that orbital of thiol group of thiopentalinvolved for Au NPs surface and when pH change from 10.2 to 6 , the amino group of the thiopental would be accepted H + and get positive charge. In present of excesscitrate at the pH of 6 , thiopental-AuNPscan be aggregated via electrostatic attraction between the citrate ions and the thiopental. So that in this study we used citrate buffer solutionfor control of pH( in the pH range of 3.0–6.0) and source of citrate (as a bridging factor). The aggregation mechanism of Au NPs is illustrated in Fig. 1. Optimization pH and time we proceeded to study the behavior of the conjugated system by modifying the pH( 7.1-5.4). The pH of an aqueous solution of0.00001M thiopental capped AuNPs was varied by direct addition of 0.05Mcitrate buffer to the solution andThe UV-Vis spectrum wasmonitored and the extinction ratio of absorbance at 600 nm to 420 nm (A600/A410) is plotted against the pH inFig. 3A. The thiopental-capped Au NPs were stable at basic and neutral conditions.When the pH of the solution was below the 6.4 , Au NPs agglomerated.the aggregation was solely due to the bridging citrate between the amine functionality.Onthe basis of this optimization experiment, the pH was set to 6.2 to achieve a best aggregationFig. 3A.When the pH was decreased immediately from 5.4 after the addition of the citrate buffer scatteringwasobserved.Fig. 3A illustrates theabsorption spectra of AuNPs at different pH value. At the concentration of sodium thiopental as 0.00001M, the extinction ratio ofA650/A520 at room temperatureexhibited a rapid increaseduring the first 1.5min,then increased gradually from 1 min to 18 min and then remained constantFig 3B. Thus, the detection time was chosen as 20 min. We choseto use the absorbance ratio at 500 and 600 wavelengths to quantify thecolor of the system,thecolor change at various sodium thiopental concentrations were monitored byUV/Vis spectroscopyfig4A.Quantitative analysis was performed by monitoringthe absorbanceat 1minute after the addition of citrate buffer Fig4B .The linear range, detection limit and reproducibilityof the method were evaluated under the optimumconditions.Thecalibration curve for sodium thiopental was linear in two ranges of( †¦Ã¢â‚¬ ¦. To †¦Ã¢â‚¬ ¦ and†¦Ã¢â‚¬ ¦ to †¦Ã¢â‚¬ ¦) with correlation coefficients 0.9981 and0.9979, respectively. The Experimental detection limit has been obtained as 2 µM. The relative standard deviation(R.S.D.) for1.0Ãâ€"10−8M thiopental measurementwas2.7% (n=11)Fig4A .when thiopental concentrationincreased above 0.0005M, scattering was observed fig3B because thiopental polymerized white citrate molecule. So that we tried paptode techniques to resolve thisproblem FigS1. Although the higher concentrations of sodium thiopental was determined by paptode, but the limit of detection was rather high (LOD 10  µM) in comparison to the spectrophotometric method. The detailed procedure for sodium thiopental determination by the paptode method is explained in supporting information. To test the selectivity of the above method for sodium thiopental, we testing the response of the assay to some potential interference species and structurally similar to the sodium thiopental such as†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.in optimum condition and different concentration .the results areshown in bar diagramFigure 8 .red barsexhibit Color changes of the solution in thepresence of various interference species at concentrations of 10mMand bluebars exhibit Color changes in presence ofinterference species at real concentration in serum ( 1M cysteine, 2M†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦), The maximum absorption wavelength of AuNPs did notchange in the presence of the tested species, Except for cysteineat concentrations of 10mM. Therefore, AuNPs had good selectivity for sodium thiopental detection in optimum condition in the serum. Colorimetric detection of sodium thiopental in serum: To validate the reliability of the proposed method for sodium thiopental detection in real samples, The unknown amounts of thiopental were added to thethree different human serum samples before samplespre-treatment .Detecting of sodium thiopental in a serum is not easy because of the serum constituents.the color of the Au NPs was not stable by the addition of the blank serum. So that it mustdiluted ten times. As regardsthe calibration curve for detection thiopental by this methodand dilution of serum and thiopental concentration in serum as a function of time varies after the usual 4.8 mg/kg induction doses [] , we can detect sodium thiopental in human serumbefore 3 hour.samples were determined by both the AuNP-based method reported herein and the standard addition method. Satisfactory results and recoveries as shown in Table 2. The satisfactory results obtained indicate that proposed sensors can be applied to real sample assays. 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